Chapter 6 Developmental and perinatal brain diseases

Publication date: 2017 Source:Handbook of Clinical Neurology, Volume 145 Author(s): Homa Adle-Biassette, Jeffery A. Golden, Brian Harding This chapter briefly describes the normal development of the nervous system, the neuropathology and pathophysiology of acquired and secondary disorders affecting the embryo, fetus, and child. They include CNS manifestations of chromosomal change; forebrain patterning defects; disorders of the brain size; cell migration and specification disorders; cerebellum, hindbrain and spinal patterning defects; hydrocephalus; secondary malformations and destructive pathologies; vascular malformations; arachnoid cysts and infectious diseases. The distinction between malformations and disruptions is important for pathogenesis and genetic counseling.
Source: Handbook of Clinical Neurology - Category: Neurology Source Type: research