Yolk Sac Erythromyeloid Progenitors Expressing Gain Of Function PTPN11 Have Functional Features Of JMML But Are Not Sufficient To Cause Disease In Mice

Conclusions: YS EMPs expressing mutant PTPN11 demonstrate functional and molecular features of JMML but do not cause disease following transplantation nor following unperturbed development. This article is protected by copyright. All rights reserved.

Source: Developmental Dynamics - October 4, 2017 Category: Molecular Biology Authors: Stefan P. Tarnawsky, Momoko Yoshimoto, Lisa Deng, Rebecca J. Chan, Mervin C. Yoder Tags: Research Article Source Type: research