Differential expression of long-term potentiation among identified inhibitory inputs to dopamine neurons

We describe a mapping of plasticity expression, mediated by different mechanisms, among three distinct GABA afferents to ventral tegmental area (VTA) dopamine neurons: the rostromedial tegmental nucleus, the nucleus accumbens, and the local GABA neurons within the VTA known to synapse on VTA dopamine neurons. This work is the first demonstration that discrete plasticity mechanisms recruit overlapping but different subsets of GABA inputs to VTA dopamine neurons.

Source: Journal of Neurophysiology - October 1, 2017 Category: Neurology Authors: Simmons, D. V., Petko, A. K., Paladini, C. A. Tags: Research Articles Source Type: research