Plasma Concentrations of Per- and Polyfluoroalkyl Substances at Baseline and Associations with Glycemic Indicators and Diabetes Incidence among High-Risk Adults in the Diabetes Prevention Program Trial

Conclusions: At baseline, several PFAS were cross-sectionally associated with small differences in markers of insulin secretion and β-cell function. However, there was limited evidence suggesting that PFAS concentrations are associated with diabetes incidence or changes in glycemic indicators during the follow-up period. https://doi.org/10.1289/EHP1612 Received: 12 January 2017 Revised: 03 August 2017 Accepted: 04 August 2017 Published: 02 October 2017 Address correspondence to E. Oken, Obesity Prevention Program, Harvard Medical School and Harvard Pilgrim HealthCare Institute, Dept. of Population Medicine, 401 Park Dr. Suite 401, Boston, MA 02215 USA. Telephone: (617) 867-4879. Email: Emily_oken@hphc.org Supplemental Material is available online (https://doi.org/10.1289/EHP1612). The authors declare they have no actual or potential competing financial interests. The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention (CDC). Use of trade names is for identification only and does not imply endorsement by the CDC, the Public Health Service, or the U.S. Department of Health and Human Services. Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information bei...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research