Urinary renin-angiotensin markers in polycystic kidney disease

In conclusion, this study shows that, despite similar circulating RAAS component levels, higher urinary excretions of angiotensinogen and renin are a unique feature of ADPKD. Future studies should address the underlying mechanism and whether this may contribute to hypertension or disease progression in ADPKD.

Source: AJP: Renal Physiology - October 1, 2017 Category: Urology & Nephrology Authors: Salih, M., Bovee, D. M., Roksnoer, L. C. W., Casteleijn, N. F., Bakker, S. J. L., Gansevoort, R. T., Zietse, R., Danser, A. H. J., Hoorn, E. J. Tags: RESEARCH ARTICLE Source Type: research