MK2 balances inflammation and cell death
Nature Cell Biology 19, 1150 (2017).
doi:10.1038/ncb3619
Author: Andrew Oberst
The cytokine tumour necrosis factor (TNF) and the toll-like receptors (TLRs) coordinate immune responses by activating inflammatory transcriptional programs, but these signals can also trigger cell death. Recent studies identify the MAP kinase substrate MK2 as a key player in determining whether cells live or die in response to TNF and TLR signalling.
Source: Nature Cell Biology - Category: Cytology Authors: Andrew Oberst Tags: News and Views Source Type: research