Keratins regulate {beta}-cell mitochondrial morphology, motility, and homeostasis [Research]

In conclusion, keratins, likely through trichoplein–mitofusin interactions, regulate both structural and dynamic functions of β-cell mitochondria, which could have implications for downstream insulin secretion.—Silvander, J. S. G., Kvarnström, S. M., Kumari-Ilieva, A., Shrestha, A., Alam, C. M., Toivola, D. M. Keratins regulate β-cell mitochondrial morphology, motility, and homeostasis.

Source: FASEB Journal - September 28, 2017 Category: Biology Authors: Silvander, J. S. G., Kvarnström, S. M., Kumari-Ilieva, A., Shrestha, A., Alam, C. M., Toivola, D. M. Tags: Research Source Type: research