Translation inhibition and stress granules in the antiviral immune response

Nature Reviews Immunology 17, 647 (2017). doi:10.1038/nri.2017.63 Authors: Craig McCormick & Denys A. Khaperskyy Efficient viral gene expression is threatened by cellular stress response programmes that rapidly reprioritize the translation machinery in response to varied environmental assaults, including virus infection. This results in inhibition of bulk synthesis of housekeeping proteins and causes the aggregation of messenger ribonucleoprotein complexes into
Source: Nature Reviews Immunology - Category: Allergy & Immunology Authors: Tags: Review Source Type: research