Mitochondrial control of immunity: beyond ATP

Nature Reviews Immunology 17, 608 (2017).
doi:10.1038/nri.2017.66

Authors: Manan M. Mehta, Samuel E. Weinberg & Navdeep S. Chandel
Mitochondria are important signalling organelles, and they dictate immunological fate. From T cells to macrophages, mitochondria form the nexus of the various metabolic pathways that define each immune cell subset. In this central position, mitochondria help to control the various metabolic decision points that determine

Source: Nature Reviews Immunology - July 3, 2017 Category: Allergy & Immunology Authors: Manan M. Mehta Samuel E. Weinberg Navdeep S. Chandel Tags: Review Source Type: research