B cell autoimmunity at the extremes

Nature Immunology 18, 1065 (2017). doi:10.1038/ni.3840 Authors: Julie Zikherman & Clifford A Lowell Caveolin-1 has a critical role in orchestrating the membrane organization of B cells. In its absence, signaling via the B cell antigen receptor and B cell tolerance are impaired, which results in autoimmunity.
Source: Nature Immunology - Category: Allergy & Immunology Authors: Tags: News and Views Source Type: research