Decreased Functional Connectivity in Schizophrenia: The Relationship between Social Functioning, Social Cognition and Graph Theoretical Network Measures

Schizophrenia is a complex disorder in which abnormalities in brain connectivity and social functioning play a central role. The aim of this study is to explore small-world network properties, and understand their relationship with social functioning and social cognition in the context of schizophrenia, by testing functional connectivity differences in network properties and its relation to clinical behavioral measures. Resting-state fMRI time series data were acquired from 23 patients diagnosed with schizophrenia and 23 healthy volunteers.
Source: Psychiatry Research: Neuroimaging - Category: Psychiatry Authors: Source Type: research