Long-Term Air Pollution Exposure and Amyotrophic Lateral Sclerosis in Netherlands: A Population-based Case –control Study

Conclusions:
Based on a large population-based case–control study, we report evidence for the association between long-term exposure to traffic-related air pollution and increased susceptibility to ALS. Our findings further support the necessity for regulatory public health interventions to combat air pollution levels and provide additional insight into the potential pathophysiology of ALS. https://doi.org/10.1289/EHP1115

Received: 19 September 2016
Revised: 31 July 2017
Accepted: 03 August 2017
Published: 27 September 2017
Address correspondence to R.C.H. Vermeulen, Division of Environmental Epidemiology, Institute for Risk Assessment Sciences (IRAS), Utrecht University, PO Box 80178, 3508 TD, Utrecht, Netherlands. Phone: [phone]. Email: [e-mail]
Supplemental Material is available online (https://doi.org/10.1289/EHP1115).
*These authors contributed equally to this work.
†Joint last authors.
J.H.V. received travel grants from Baxter. G.H. received grants from European Union. L.H.v.d.B. received travel grants and consultancy fees from Baxter and Biogen Idec, and he serves on scientific advisory boards for Cytokinetics, Biogen Idec, and Baxalta.
All other authors declare they have no actual or potential competing financial interests.
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Source: EHP Research - September 27, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research