Modification of population based arterial input function to incorporate individual variation

This technical note describes how to modify a population-based arterial input function to incorporate variation among the individuals. In DCE-MRI, an arterial input function (AIF) is often distorted by pulsated inflow effect and noise. A population-based AIF (pAIF) has high signal-to-noise ratio (SNR), but cannot incorporate the individual variation. AIF variation is mainly induced by variation in cardiac output and blood volume of the individuals, which can be detected by the full width at half maximum (FWHM) during the first passage and the amplitude of AIF, respectively.

Source: Magnetic Resonance Imaging - September 25, 2017 Category: Radiology Authors: Harrison Kim Tags: Technical note Source Type: research