A new class of cubic SPIONs as a dual-mode T1 and T2 contrast agent for MRI

In this study, we (a) synthesized a new class of cubic SPIONs as a dual-mode contrast agent in MRI and (b) showed the in-vivo feasibility of these nanaoparticles as a simultaneous positive and negative contrast agent. Relaxation properties and contrast enhancement analysis of the synthesized SPIONs with two different shapes (cubic vs. spherical) and three different sizes 7nm, 11nm, and 14nm were investigated to evaluate contrast enhancement in-vitro.
Source: Magnetic Resonance Imaging - Category: Radiology Authors: Tags: Original contribution Source Type: research