Gonadal soma controls ovarian follicle proliferation through Gsdf in zebrafish

Conclusions: In zebrafish, gsdf regulates ovarian follicle maturation and expression of genes for steroid biosynthesis, obesity, diabetes, and female fertility, leading to ovarian and extra‐ovarian phenotypes that mimic human polycystic ovarian syndrome (PCOS), suggesting a role for a related TGFB signaling molecule in the etiology of PCOS. Developmental Dynamics, 2017. © 2017 Wiley Periodicals, Inc.

Source: Developmental Dynamics - September 25, 2017 Category: Molecular Biology Authors: Yi ‐Lin Yan, Thomas Desvignes, Ruth Bremiller, Catherine Wilson, Danielle Dillon, Samantha High, Bruce Draper, Charles Loren Buck, John Postlethwait Tags: Research Article Source Type: research