Hepatitis B virus reactivation after heart transplant: incidence and clinical impact
Hepatitis B virus (HBV) infection remains a major public health problem with about 248 million people chronically infected [1]. Sexual and parenteral transmission occurs not only from HBV surface antigen (HBsAg) positive subjects, but also from HBsAg-negative donors [2,3] with the so called “occult hepatitis B infection (OBI)”. OBI consists in the long-term persistence of viral genomes (covalently closed circular DNA and/or messenger RNA) in hepatocytes and peripheral blood mononuclear cells (PBMCs), very low (
Source: Journal of Clinical Virology - Category: Virology Authors: Martina Vitrone, Domenico Iossa, Luca Rinaldi, Pia Clara Pafundi, Rosa Molaro, Antonio Parrella, Roberto Andini, Enrico Ragone, Ciro Maiello, Rosa Zampino, Emanuele Durante-Mangoni Tags: Full length article Source Type: research
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