Parental Age and Risk of Infant Leukaemia: A Pooled Analysis

ConclusionThis study demonstrates increased risk of infant ALL in relation to young paternal age. Given record linkage, there is little concern with recall or selection bias, although data are lacking on MLL gene status and other potentially important variables. Parent of origin effects, de novo mutations, and/or carcinogenic exposures may be involved in IL aetiology.

Source: Paediatric and Perinatal Epidemiology - September 1, 2017 Category: Perinatology & Neonatology Authors: Erin L. Marcotte, Todd E. Druley, Kimberly J. Johnson, Michaela Richardson, Julie Behren, Beth A. Mueller, Susan Carozza, Colleen McLaughlin, Eric J. Chow, Peggy Reynolds, Logan G. Spector Tags: Original Article Source Type: research