Segmenting Hippocampal Subfields from 3T MRI with Multi-modality Images

The hippocampus plays an important role in both episodic and long-term memory encoding and retrieval (Zeineh et  al., 2003; Squire et al., 2004; Moscovitch et al., 2006). Clinically, hippocampal volumetric change is an important biomarker for early diagnosis of many neurological diseases, including Alzheimer’s Disease (AD) and schizophrenia (Bobinski et al., 1996; Csernansky et al., 1998; Jack et al., 2000; De Leon et al., 2006; Schuff et al., 2009). Previously, most automatic hippocampus segmentation techniques treated the hippocampus as a whole structure (Fischl et al., 2002; Smith et al., 2004; Patenaude et al., 2011; Zhang et al., 2012; Wu et al., 2014; Ma et al., 2015).

Source: Medical Image Analysis - September 21, 2017 Category: Radiology Authors: Zhengwang Wu, Yaozong Gao, Feng Shi, Guangkai Ma, Valerie Jewells, Dinggang Shen Source Type: research