Splicing and transcription touch base: co-transcriptional spliceosome assembly and function

Nature Reviews Molecular Cell Biology 18, 637 (2017).
doi:10.1038/nrm.2017.63

Authors: Lydia Herzel, Diana S. M. Ottoz, Tara Alpert & Karla M. Neugebauer
Several macromolecular machines collaborate to produce eukaryotic messenger RNA. RNA polymerase II (Pol II) translocates along genes that are up to millions of base pairs in length and generates a flexible RNA copy of the DNA template. This nascent RNA harbours introns that are removed

Source: Nature Reviews Molecular Cell Biology - August 9, 2017 Category: Cytology Authors: Lydia Herzel Diana S. M. Ottoz Tara Alpert Karla M. Neugebauer Tags: Review Source Type: research