Racial and ethnic differences in preterm birth: A complex, multifactorial problem

Preterm birth remains the leading cause of morbidity and mortality among nonanomalous neonates, and is a major public health problem. Non-Hispanic black women have a 2-fold greater risk for preterm birth compared with non-Hispanic white race. The reasons for this disparity are poorly understood and cannot be explained solely by sociodemographic factors. Underlying factors including a complex interaction between maternal, paternal, and fetal genetics, epigenetics, the microbiome, and these sociodemographic risk factors likely underlies the differences between racial groups, but these relationships are currently poorly understood.

Source: Seminars in Perinatology - September 20, 2017 Category: Perinatology & Neonatology Authors: Tracy A. Manuck Source Type: research