Prevalence of transactive response DNA ‐binding protein 43 (TDP‐43) proteinopathy in cognitively normal older adults: systematic review and meta‐analysis

ConclusionsDifferent methodology to access TDP‐43, and also differences in lifestyle and genetic factors across different populations could explain our results. Standardization of TDP‐43 measurement, and future studies about the impact of genetic and lifestyle characteristics on the development of neurodegenerative diseases are needed.

Source: Neuropathology and Applied Neurobiology - September 20, 2017 Category: Neurology Authors: C. Nascimento, A. T. Di Lorenzo Alho, C. Bazan Concei ção Amaral, R. E. P. Leite, R. Nitrini, W. Jacob‐Filho, C. A. Pasqualucci, S. R. K. Hokkanen, S. Hunter, H. Keage, G. G. Kovacs, L. T. Grinberg, C. K. Suemoto Tags: Original Article Source Type: research