Neurodevelopmental disorders: A transcription-targeting target

Nature Reviews Neuroscience 18, 572 (2017). doi:10.1038/nrn.2017.123 Author: Natasha Bray Fragile X mental retardation protein (FMRP) represses the transcription of many target genes, including genes that encode chromatin-associated proteins. Loss of FMRP leads to fragile X syndrome (FXS); however, whether misregulation of chromatin-associated proteins contributes to FXS is unclear. Korb et al. showed that
Source: Nature Reviews Neuroscience - Category: Neuroscience Authors: Tags: Research Highlight Source Type: research