Does Beclin-1 have a role in hepatocellular carcinoma in Egyptian patients?
Conclusion: Beclin-1 is a good prognostic marker in view of the association between low Beclin-1 expression and high lymphovascular invasion and advanced pathological stage. Moreover, there is a reciprocal talk between Beclin-1 and Bcl-2, as under stressful conditions (HCC or cirrhosis) Beclin-1 dissociated from the Beclin-1–Bcl-2 complex, modulating the tumor suppressor action of Beclin-1.
Source: Egyptian Journal of Pathology - Category: Pathology Tags: Original Articles Source Type: research
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