Immunohistochemical expression of Bmi-1, S100A4, and claudin-1 in breast cancer

This study aimed to assess the expression of Bmi-1, S100A4, and claudin-1 in immunostained specimens of breast cancer and correlate their immunohistochemical expression with the clinicopathological parameters to identify their impact on tumor behavior and carcinogenesis. Materials and methods: Bmi-1, S100A4, and claudin-1 immunohistochemical expressions were evaluated and analyzed in 50 paraffin-embedded specimens of breast cancer. Results: Bmi-1, S100A4, and claudin-1 expression was found in 58, 44, and 34%, respectively, of the studied cases. There was a significant positive association between Bmi-1 expression and tumor grade (P
Source: Egyptian Journal of Pathology - Category: Pathology Tags: Original Articles Source Type: research