Rhabdomyolysis after risperidone

Rhabdomyolysis is a potentially life‐threatening syndrome that reflects lysis of muscle fibers secondary to disruption of the calcium homeostasis in muscle cells. This results in leakage of toxic cellular contents into the systemic circulation, eventually leading to muscle destruction and fiber necrosis. Patients with the condition usually exhibit significantly elevated serum creatine kinase.
Source: The Brown University Psychopharmacology Update - Category: Psychiatry Authors: Tags: Drug ‐Drug Interactions Source Type: research