Randomized trial of omega-3 for autism spectrum disorders: Effect on cell membrane composition and behavior

A high ω6/ω3 ratio [fatty acid (FA) index] in the cell membrane has been associated with inadequate brain development. It has started to be used as a biomarker of treatment efficacy in human diseases. The aim of this study was to investigate if omega-3 supplementation improves erythrocyte membrane ω6/ω 3, plasma antioxidant status (TAS) and autistic behaviors. A randomized, crossover, placebo-controlled study was designed to investigate the effect of 8 weeks of supplementation with ω3 (962mg/d and 1155mg/d for children and adolescents, respectively).

Source: European Neuropsychopharmacology - September 18, 2017 Category: Psychiatry & Psychology Authors: Mara Parellada, Cloe Llorente, Rosa Calvo, Silvia Gutierrez, Luisa L ázaro, Montserrat Graell, Maria Guisasola, Maria Luisa Dorado, Leticia Boada, Jose Romo, Elena Dulin, Inmaculada Sanz, Celso Arango, Carmen Moreno Source Type: research