Validating the Association between Plasma Tumour Necrosis Factor Receptor 1 Levels and the Presence of Renal Injury and Functional Decline in Patients with Type 2 Diabetes

Elevated plasma soluble tumour necrosis factor receptor 1(TNFR1) predicts long-term progression of chronic kidney disease. We investigated the association between elevated TNFR1 and the presence of renal disease in patients with Type 2 diabetes mellitus registering a haemoglobin A1c (HbA1c)>48mmol/mol despite medical therapy.

Source: Journal of Diabetes and Its Complications - September 15, 2017 Category: Endocrinology Authors: Alison Doody, Sabrina Jackson, Jessie A. Elliott, Ronan J. Canavan, C. Godson, David Slattery, Patrick J. Twomey, Malachi J. McKenna, Carel W. le Roux, Neil G. Docherty Source Type: research