Phase 2a Clinical Trial of Mitochondrial Protection (Elamipretide) During Stent Revascularization in Patients With Atherosclerotic Renal Artery Stenosis [Peripheral Vascular Disease]

Conclusions— Adjunctive elamipretide during PTRA was associated with attenuated postprocedural hypoxia, increased RBF, and improved kidney function in this pilot trial. These data support a role for targeted mitochondrial protection to minimize procedure-associated ischemic injury and to improve outcomes of revascularization for human atherosclerotic renal artery stenosis. Clinical Trial Registration— URL: https://www.clinicaltrials.gov. Unique identifier: NCT01755858.
Source: Circulation: Cardiovascular Interventions - Category: Cardiology Authors: Tags: Nephrology and Kidney, Imaging, Atherosclerosis, Peripheral Vascular Disease, Stenosis Source Type: research