Basal ganglia and ventricle volume in first-episode psychosis. A family and clinical study

Patients with first-episode psychosis (FEP) exhibit considerable heterogeneity in subcortical brain volumes. We sought to compare ventricle and basal ganglia volumes in FEP patients (n = 50) with those in unaffected relatives (n = 21) and healthy controls (n = 24). Participants were assessed with a semistructured interview and underwent structural magnetic resonance imaging (MRI). Patients had significantly larger left lateral, right lateral and third ventricle volumes than their siblings and larger third ventricle volumes than controls.

Source: Psychiatry Research: Neuroimaging - September 15, 2017 Category: Psychiatry Authors: Manuel J. Cuesta, Pablo Lecumberri, Teresa Cabada, Lucia Moreno-Izco, Mar ía Ribeiro, Jose M. López-Ilundain, Victor Peralta, Ruth Lorente-Omeñaca, Ana Ma Sánchez-Torres, Marisol Gómez Source Type: research