Mixed infections in tuberculosis: The missing part in a puzzle
The mixed strains infection phenomenon is a major problem posing serious challenges in control of tuberculosis (TB). In patients with mixed infection, several different strains of Mycobacterium tuberculosis can be isolated simultaneously. Although different genotyping methods and various molecular approaches can be employed for detection of mixed infection in clinical samples, the MIRU-VNTR technique is more sensitive with higher discriminative power than many widely used techniques. Furthermore, the recent introduction of whole genome sequencing (WGS) promises to reveal more details about mixed infection with high resolution.
Source: Tuberculosis - Category: Respiratory Medicine Authors: Samira Tarashi, Abolfazl Fateh, Mehdi Mirsaeidi, Seyed Davar Siadat, Farzam Vaziri Tags: Review Source Type: research
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