Building and validating a prediction model for paediatric type 1 diabetes risk using next generation targeted sequencing of class II HLA genes

ConclusionThrough both empirical and biological validation, we have established a prediction model for estimating lifetime T1D risk, using class II HLA. This prediction model should prove useful for future investigations to identify high‐risk subjects for prevention research in high‐risk populations.

Source: Diabetes/Metabolism Research and Reviews - September 15, 2017 Category: Endocrinology Authors: Lue Ping Zhao, Annelie Carlsson, Helena Elding Larsson, Gun Forsander, Sten A. Ivarsson, Ingrid Kockum, Johnny Ludvigsson, Claude Marcus, Martina Persson, Ulf Samuelsson, Eva Örtqvist, Chul‐Woo Pyo, Hamid Bolouri, Michael Zhao, Wyatt C. Nelson, Daniel Tags: RESEARCH ARTICLE Source Type: research