Climbing fibers predict movement kinematics and performance errors

This article demonstrates that complex spike (CS) discharge of cerebellar Purkinje cells encodes multiple parameters of movement, including motor errors and kinematics. The CS firing is not driven by error or kinematic events; instead it provides a linear representation of each parameter. In contrast with the view that CSs carry feedback signals, the CSs are predominantly predictive of upcoming position errors and kinematics. Therefore, climbing fibers carry multiple and predictive signals for online motor control.

Source: Journal of Neurophysiology - September 14, 2017 Category: Neurology Authors: Streng, M. L., Popa, L. S., Ebner, T. J. Tags: Research Articles Source Type: research