Outcomes of congenital cytomegalovirus disease following maternal primary and non-primary infection

Congenital cytomegalovirus (cCMV) infection is a common cause of neurodevelopmental disabilities [1]. Unlike other perinatal infections as congenital rubella or toxoplasmosis, CMV maternal immunity acquired prior to conception does not ensure a complete protection of fetus from infection [2 –6]. Approximately 40% of women experiencing a CMV primary infection during pregnancy will transmit virus to their fetus. Of the infants infected in utero, about 10% will exhibit some symptoms at birth that are consistent with cCMV symptomatic infection [6].

Source: Journal of Clinical Virology - September 13, 2017 Category: Virology Authors: Antonietta Giannattasio, Pasquale Di Costanzo, Arianna De Matteis, Paola Milite, Daniela De Martino, Laura Bucci, Maria Rosaria Augurio, Carmela Bravaccio, Teresa Ferrara, Letizia Capasso, Francesco Raimondi Tags: Full length article Source Type: research