Dynamic hyperinflation and exercise limitations in obese asthmatic women

This study shows that dynamic hyperinflation is a common condition in obese asthmatics; they have reduced fitness for activities of daily living compared to nonobese asthmatics. However, peripheral limitation was the main factor associated with reduced capacity of exercise in these patients.
NEW & NOTEWORTHY This is the first study to investigate the occurrence of dynamic hyperinflation (DH) in obese asthmatics. Our results demonstrate that obese asthmatics present a higher frequency and intensity of DH than nonobese asthmatics. We also show that physical deconditioning in this population is linearly associated with cardiac (O2 pulse), respiratory (DH), and peripheral muscle (resistance) limitation. However, multiple linear regression demonstrated that peripheral muscle limitation may explain the exercise limitation in this population.

Source: Journal of Applied Physiology - September 14, 2017 Category: Physiology Authors: Ferreira, P. G., Freitas, P. D., Silva, A. G., Porras, D. C., Stelmach, R., Cukier, A., Fernandes, F. L. A., Martins, M. A., Carvalho, C. R. F. Tags: RESEARCH ARTICLE Source Type: research