Random squat/stand maneuvers: a novel approach for assessment of dynamic cerebral autoregulation?

In conclusion, RFSSMs are an effective and noninvasive method of assessing dCA. There is no difference in the ARI estimates in comparison with FFSSMs. Although FFSSMs have been well tolerated previously, RFSSMs are preferred by healthy subjects and thus may be better tolerated by a patient population in a clinical setting.
NEW & NOTEWORTHY RFSSMs provided comparable estimates of autoregulatory indices to FFSSMs. Instead of point estimates at the driven frequency, RFSSMs generate a broader power spectrum of changes in arterial blood pressure and cerebral blood flow velocity, allowing direct comparison with spontaneous fluctuations through transfer function analysis. Moreover, random-frequency SSMs are preferred by participants. They are a novel tool by which larger blood pressure oscillations can be elicited for the reliable measurement of dynamic cerebral autoregulation.

Source: Journal of Applied Physiology - September 14, 2017 Category: Physiology Authors: Barnes, S. C., Ball, N., Panerai, R. B., Robinson, T. G., Haunton, V. J. Tags: INNOVATIVE METHODOLOGY Source Type: research