Non-Parametric GraphNet-Regularized Representation of dMRI in Space and Time

Probing brain tissue structure with time-dependent properties of the diffusion MRI (dMRI) signal is gaining momentum in the dMRI community (see e.g. Moonen et  al., 1991; Le Bihan, 1995; Assaf et al., 1998; Novikov et al., 2014; De Santis et al., 2016; Ning et al., 2016; Fieremans et al., 2016). Yet, effectively representing the four-dimensional dMRI signal – varying over three-dimensional q-space and diffusion time – is still a sought-after a nd unsolved challenge. To specifically represent the dMRI signal in this qτ-space, which has been coined by Novikov et al.

Source: Medical Image Analysis - September 13, 2017 Category: Radiology Authors: Rutger H.J. Fick, Alexandra Petiet, Mathieu Santin, Anne-Charlotte Philippe, Stephane Lehericy, Rachid Deriche, Demian Wassermann Source Type: research