Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides

Nature Biotechnology 35, 845 (2017). doi:10.1038/nbt.3948 Authors: Naoki Iwamoto, David C D Butler, Nenad Svrzikapa, Susovan Mohapatra, Ivan Zlatev, Dinah W Y Sah, Meena, Stephany M Standley, Genliang Lu, Luciano H Apponi, Maria Frank-Kamenetsky, Jason Jingxin Zhang, Chandra Vargeese & Gregory L Verdine
Source: Nature Biotechnology - Category: Biotechnology Authors: Tags: Research Source Type: research
More News: Biotechnology