[Comment] Unravelling neurodegeneration in multiple sclerosis

Neurodegeneration is postulated to be a major contributor to neurological disability in multiple sclerosis and might be the dominant process underlying progressive multiple sclerosis. Whether neurodegeneration is an independent process in patients with multiple sclerosis or its occurrence is secondary to inflammation remains unknown.1 Current therapies, focused on immune modulation, are generally less effective in the progressive forms than in the relapsing remitting forms of the disease. Therefore, understanding neurodegeneration might be fundamental to determining how to prevent neurological disability in all patients with multiple sclerosis, but especially in those in whom a progressive disease course dominates.
Source: Lancet Neurology - Category: Neurology Authors: Tags: Comment Source Type: research