SPOP tips the balance of BETs in cancer
Nature Medicine 23, 1014 (2017).
doi:10.1038/nm.4398
Authors: Katie A Fennell & Mark A Dawson
Cancer-associated mutations in speckle-type POZ (pox virus and zinc-finger) protein confer neomorphic activity, altering its substrate affinities and its response to bromodomain and extraterminal inhibitors in prostate and endometrial cancer.
Source: Nature Medicine - Category: General Medicine Authors: Katie A Fennell Mark A Dawson Tags: News and Views Source Type: research