Atropinic (Anticholinergic) Burden in Antipsychotic ‐Treated Patients
This study showed high values of anticholinergic burden in patients receiving antipsychotics. Thus, considering the potential noxious clinical impact of atropinic properties on cognitive functions, an appropriate approach should be to reduce prescription of antipsychotics with a high anticholinergic burden but also coprescription of other frequently associated atropinic drugs, like antiparkinsonians, H1 antihistamines or imipraminic antidepressants in these patients.
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Source: Fundamental and Clinical Pharmacology - Category: Drugs & Pharmacology Authors: Fran çois Montastruc, Justine Benevent, Anthony Touafchia, Leila Chebane, Mélanie Araujo, Emmanuelle Guitton‐Bondon, Geneviève Durrieu, Christophe Arbus, Laurent Schmitt, Bernard Begaud, Jean‐Louis Montastruc Tags: Original Article Source Type: research