BK virus replication in renal transplant recipients: Analysis of potential risk factors may contribute in reactivation

Although the name of BK virus has rarely been mentioned as a pathogenic agent in some extra-renal human diseases, it has been strongly known as a significant viral infection related to nephropathy and renal graft-failure in kidney transplant recipients [1]. The first isolation of BK virus was carried out by Gardner et al. in 1971 [2], and thereafter its clinical importance was demonstrated by Mackenzie et al. in 1978 [3]. It has been reported that 60-90% of healthy populations become seropositive by the age of 10 [4 –7].

Source: Journal of Clinical Virology - September 8, 2017 Category: Virology Authors: Mohammad Shenagari, Ali Monfared, Hadise Eghtedari, Aydin Pourkazemi, Tolou Hasandokht, Masoud Khosravi, Babak Asharfkhani Source Type: research