Adventitial tertiary lymphoid organ classification in human atherosclerosis

Atherosclerosis is a chronic inflammatory disease of the arterial wall. Adjacent to lamina intima lesion progression, a cellular compound develops in the lamina adventitia, defined as tertiary lymphoid organs (TLO) in mice. But in human system, it remains unknown whether these adventitial cellular accumulations represent these highly organized immunological structures.

Source: Cardiovascular Pathology - September 7, 2017 Category: Cardiology Authors: Mohammadreza Akhavanpoor, Christian A. Gleissner, Hamidreza Akhavanpoor, Felix Lasitschka, Andreas O. Doesch, Hugo A. Katus, Christian Erbel Tags: Original Article Source Type: research