Methylglyoxal attenuates insulin signaling and downregulates the enzymes involved in cholesterol biosynthesis

Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00305F, PaperArati Deshmukh, Shakuntala Bai, T Aarthy, Rubina S Kazi, Reema Banarjee, Rajeshwari Rathore, MV Vijayakumar , Hirekodathakallu V Thulasiram, Manoj Kumar Bhat, Mahesh J Kulkarni Methylglyoxal (MG) is a highly reactive dicarbonyl, known to be elevated in hyperglycemic condition of diabetes and is implicated in development of diabetic complications. Therefore, the current study investigates the... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Molecular Biosystems - Category: Molecular Biology Authors: Source Type: research