Anterior cingulate cortex grey matter volume abnormalities in adolescents with PTSD after childhood sexual abuse

Adverse childhood experiences (ACE) substantially increase the risk of later psychiatric and somatic pathology. While neurobiological factors are likely to play a mediating role, specific insights are lacking. The scarce neuroimaging studies in traumatised pediatric populations have provided inconsistent results, potentially due to the inclusion of different types of trauma. To further improve our understanding of the neurobiology of pediatric psychotrauma, this study seeks to investigate abnormalities in grey matter volume (GMV) in a homogeneous group of adolescents with posttraumatic stress disorder (PTSD) due to childhood sexual abuse (CSA) and the relationship between GMV and symptom severity.

Source: European Neuropsychopharmacology - September 6, 2017 Category: Psychiatry & Psychology Authors: Mirjam A. Rinne-Albers, J.  Nienke Pannekoek, Marie-José van Hoof, Natasja D. van Lang, Francien Lamers-Winkelman, Serge A. Rombouts, Nic J. van der Wee, Robert R. Vermeiren Source Type: research