Decreased PGF may contribute to trophoblast dysfunction in fetal growth restriction

In conclusion, our data suggested that the PGF expression was dysregulated, and disrupted PGF/FLT1 signaling in trophoblast might contribute to placenta dysfunction in FGR. Thus, our results support the significant role of PGF in the pathogenesis of FGR.

Source: Reproduction - September 5, 2017 Category: Reproduction Medicine Authors: Wu, W.-B., Xu, Y.-Y., Cheng, W.-W., Yuan, B., Zhao, J.-R., Wang, Y.-L., Zhang, H.-J. Tags: Research Source Type: research