Relative contributions from the ventricle and arterial tree to arterial pressure and its amplification: an experimental study

This study offers the first comprehensive investigation of contributors to hypertensive pressure and its propagation throughout the arterial tree. Importantly, ventricular inotropy plays a crucial role in the amplification of peripheral pressure wave, which offers opportunity for noninvasive assessment of ventricular health. NEW & NOTEWORTHY The present study distinguishes contributions from cardiac and arterial parameters to elevated blood pressure and pressure amplification. Most importantly, it offers the first evidence that ventricular inotropy, an indicator of ventricular function, is an independent determinant of pressure amplification and could be measured with such established devices such as the SphygmoCor.

http://ajpheart.physiology.org/cgi/content/abstract/313/3/H558?rss=1

Source: AJP: Heart and Circulatory Physiology - September 5, 2017 Category: Cardiology Authors: Gaddum, N., Alastruey, J., Chowienczyk, P., Rutten, M. C. M., Segers, P., Schaeffter, T. Tags: RESEARCH ARTICLE Source Type: research