Editorial commentary: QTdrugs: From electrocardiographic intervals to prevention of sudden cardiac death

I am pleased to comment on the article of Woosley et al. [1] published in this issue of TCM. The QT interval represents both the ventricular depolarization (QRS complex) and repolarization (ST segment and T wave). When depolarization is normal (QRS complexes of normal duration), we used it as a surrogate to measure electrical recovery of ventricular myocardium [2]. QT interval varies inversely with heart rate and therefore the clinical parameter we used is the corrected QT interval or QTc; usually using the formula described by Henry Cuthbert Bazett from Oxford in 1920 [3] and modified to its actual form in 1947 by Taran and Szilagyi [4].
Source: Trends in Cardiovascular Medicine - Category: Cardiology Authors: Source Type: research