Application of Gaussia luciferase in bicistronic and non-conventional secretion reporter constructs

Conclusions:
Due to its secretion via multiple secretion pathways GLUC can find multiple applications as a research tool to study classical and non-conventional secretion. As GLUC can also be released from a reporter construct by internal signal peptide-mediated secretion it can be incorporated in a novel bicistronic secretion system.

Source: BMC Biochemistry - July 9, 2014 Category: Biochemistry Authors: Christin LuftJamie FreemanDavid ElliottNadia Al-TamimiJanos Kriston-ViziJacob HeintzeIda LindenschmidtBrian SeedRobin Ketteler Source Type: research