Improved clonality detection in B ‐cell lymphoma using a semi‐nested modification of the BIOMED‐2 PCR assay for IGH rearrangement: A paraffin‐embedded tissue study

In conclusion, tumor clonality may be detected in nearly 90% of B‐cell lymphoma cases with semi‐nested BIOMED‐2. This ancillary assay may be useful when the standard BIOMED‐2 fails to detect clonality in histopathologically suspected B‐cell lymphomas.

Source: Pathology International - September 3, 2017 Category: Pathology Authors: Yuma Sakamoto, Ayako Masaki, Satsuki Aoyama, Shusen Han, Kosuke Saida, Kana Fujii, Hisashi Takino, Takayuki Murase, Shinsuke Iida, Hiroshi Inagaki Tags: Original Article Source Type: research