Fluid Resuscitation in Septic Shock: The Effect of Increasing Fluid Balance on Mortality

Conclusion:
In patients with septic shock resuscitated according to current guidelines, a more positive fluid balance at 24 hours is associated with an increase in the risk of mortality. Optimal survival occurred at neutral fluid balance and up to 6-L positive fluid balance at 24 hours after the development of septic shock.

Source: Journal of Intensive Care Medicine - July 8, 2014 Category: Intensive Care Authors: Sadaka, F., Juarez, M., Naydenov, S., O'Brien, J. Tags: Review of a Large Clinical Series Source Type: research